Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p059 | (1) | WCRB2014

Importance of amino acids in the development of preimplantation mouse embryo

Zamfirescu Radu , Shreedharan Salini , Zada Mark , Morris Michael , Day Margot L

The composition of the external environment can have a significant impact on intracellular signaling pathways during early embryonic development. Components of the culture media, especially amino acids, are known to improve embryo development. We have shown that L-proline and L-glutamine improve development to the blastocyst stage by acting in a growth factor-like way. The aim of this study is to investigate the effect of amino acids on signaling pathways in the...